Copper-Catalyzed Reductive Trifluoromethylation of Alkyl Iodides with Togni’s Reagent
[cite]10.1021/acs.orglett.8b02005[/cite]
Controlling an organic synthesis robot with machine learning to search for new reactivity
Lee Cronin Lab
[cite]10.1038/s41586-018-0307-8[/cite]
Exploration of the Synthetic Potential of Electrophilic Trifluoromethylthiolating and Difluoromethylthiolating Reagents
[cite]10.1002/anie.201805859[/cite]
Pd-PEPPSI-IPentAn Promoted Deactivated Amination of Aryl Chlorides with Amines under Aerobic Conditions
[cite]10.1021/acs.joc.8b01205[/cite]
Bench-Stable Transfer Reagent Facilitates the Generation of Trifluoromethyl-sulfonimidamides
[cite]10.1021/acs.joc.8b01244[/cite]
De Novo Design, Synthesis, and Biological Evaluation of 3,4-Disubstituted Pyrrolidine Sulfonamides as Potent and Selective Glycine Transporter 1 Competitive Inhibitors
An unusual bioisostere phenyl
[cite]10.1021/acs.jmedchem.8b00295[/cite]
Designing Algorithms To Aid Discovery by Chemical Robots
Lee Cronin Lab
[cite]10.1021/acscentsci.8b00176[/cite]
Radical Chlorodifluoromethylation: Providing a Motif for (Hetero)arene Diversification
[cite]10.1021/acs.orglett.8b01249[/cite]
Synthesis of (+)-Vitepyrroloid A and (+)-Vitepyrroloid B by Late-Stage Ni-Catalyzed C(sp2)–C(sp3) Cross-Electrophile Coupling
[cite]10.1021/acs.joc.8b00882[/cite]
Nickel-Catalyzed Reductive Cross-Coupling of Aryl Halides with Monofluoroalkyl Halides for Late-Stage Monofluoroalkylation
[cite]10.1002/anie.201803228[/cite]
Direct photolysis mechanism of pesticides in water
[cite]10.1584/jpestics.D17-081[/cite]
Decarboxylative Trifluoromethylation of Aliphatic Carboxylic Acids
[cite]10.1021/jacs.8b02650[/cite]
Synthesis of dibenzothiazines from sulfides by one-pot N,O-transfer and intramolecular C–H amination
[cite]10.1039/C8GC01057A[/cite]
Polycyclic Sulfoximines as New Scaffolds for Drug Discovery
[cite]10.1021/acscombsci.7b00150[/cite]
Predicting Reaction Performance in C−N Cross-Coupling Using Machine Learning
[Merck, Abigail G. Doyle]
[cite]10.1126/science.aar5169[/cite]
Chemical probes and drug leads from advances in synthetic planning and methodology
[cite]10.1038/nrd.2018.53[/cite]
Protecting Group Free Radical C-H Trifluoromethylation of Peptides
[cite]10.1039/C8SC00368H[/cite]
Deoxyfluorination with Sulfonyl Fluorides: Navigating Reaction Space with Machine Learning
[cite]10.1021/jacs.8b01523[/cite]
Elucidating the Role of the Boronic Esters in the Suzuki–Miyaura Reaction: Structural, Kinetic, and Computational Investigations
from the Scott E. Denmark group
[cite]10.1021/jacs.8b00400[/cite]
Nickel‐Catalyzed Umpolung Arylation of Ambiphilic α‐Bromoalkyl Boronic Esters
[cite]10.1002/anie.201712428[/cite]
Multimetallic Ni- and Pd-Catalyzed Cross-Electrophile Coupling To Form Highly Substituted 1,3-Dienes
[cite]10.1021/jacs.7b13601[/cite]
A platform for automated nanomole-scale reaction screening and micromole-scale synthesis in flow
[Pfizer]
[cite]10.1126/science.aap9112[/cite]
Analysis of US FDA-Approved Drugs Containing Sulfur Atoms
[cite]10.1007/s41061-018-0184-5[/cite]
Digitization of multistep organic synthesis in reactionware for on-demand pharmaceuticals
Lee Cronin Lab
[cite]10.1126/science.aao3466[/cite]