Acoustic Droplet Ejection Enabled Automated Reaction Scouting
[Dömling lab with Astra-Zeneca]
[cite]10.1021/acscentsci.8b00782[/cite]
The Pharmaceutical Industry in 2018. An Analysis of FDA Drug Approvals from the Perspective of Molecules
[cite]10.3390/molecules24040809[/cite]
How to explore chemical space using algorithms and automation
[Lee Cronin lab]
[cite]10.1038/s41570-018-0066-y[/cite]
High Throughput Strategies for the Discovery and Optimization of Catalytic Reactions
[cite]10.1002/anie.201812534[/cite]
Ir-Catalyzed, ß-Selective C(sp3)–H Silylation of Aliphatic Amines To Form Silapyrrolidines and 1,2-Amino Alcohols
[cite]10.1021/jacs.8b10428[/cite]
Nickel‐Catalyzed Mizoroki–Heck‐Type Reactions of Unactivated Alkyl Bromides
[cite]10.1002/anie.201810757[/cite]
Stereoselective Preparation of a-C-Vinyl/Aryl Glycosides via Nickel-Catalyzed Reductive Coupling of Glycosyl Halides with Vinyl and Aryl Halides
[cite]10.1021/acs.orglett.8b03567[/cite]
Synthesis of Electron-Deficient Heteroaromatic 1,3-Substituted Cyclobutyls via Zinc Insertion/Negishi Coupling Sequence under Batch and Automated Flow Conditions
[cite]10.1021/acs.orglett.8b03588[/cite]
Direct Primary Amination of Alkylmetals with NH-Oxaziridine
[cite]10.1021/acs.orglett.8b03734[/cite]
Chemoselective α,β‐Dehydrogenation of Saturated AmidesChemoselective α,β‐Dehydrogenation of Saturated Amides
[cite]10.1002/anie.201808794[/cite]
isible-Light-Driven External-Reductant-Free Cross-Electrophile Couplings of Tetraalkyl Ammonium Salts
[cite]10.1021/jacs.8b08792[/cite]
Synthesis and Derivatization of 1,1‐[18F]Difluorinated Alkenes
[cite]10.1002/anie.201810413[/cite]
C−I‐Selective Cross‐Coupling Enabled by a Cationic Palladium TrimerC−I‐Selective Cross‐Coupling Enabled by a Cationic Palladium Trimer
[cite]10.1002/anie.201811380[/cite]
Chemoselective Aza-[4+3]-annulation of N-Perfluoroalkyl-1,2,3-triazoles with 1,3-Dienes: Access to N-Perfluoroalkyl-Substituted Azepines
[cite]10.1021/acs.joc.8b02472[/cite]
Advances in Lead Generation
[cite]10.1016/j.bmcl.2018.12.001[/cite]
Amination of Phosphorodiamidate-Substituted Pyridines and Related N-Heterocycles with Magnesium Amides
[cite]10.1021/acs.orglett.8b03698[/cite]
Highly Chemoselective Deprotection of the 2,2,2-Trichloroethoxycarbonyl (Troc) Protecting Group
[cite]10.1021/acs.orglett.8b03642[/cite]
Synthesis of CMe2CF3-Containing Heteroarenes via Tandem 1,1-Dimethyltrifluoroethylation and Cyclization of Isonitriles
[cite]10.1021/acs.joc.8b02506[/cite]
Sustainable Alkylation of Unactivated Esters and Amides with Alcohols Enabled by Manganese Catalysis
[cite]10.1021/acs.orglett.8b03184[/cite]
Silyldefluorination of Fluoroarenes by Concerted Nucleophilic Aromatic Substitution
[cite]10.1002/anie.201808646[/cite]
Photochemical generation of radicals from alkyl electrophiles using a nucleophilic organic catalyst
[cite]10.1038/s41557-018-0173-x[/cite]
Computational Method to Evaluate Progress in Lead Optimization
[cite]10.1021/acs.jmedchem.8b01626[/cite]