Mois : octobre 2018

Catalytic Deprotonative α-Formylation of Heteroarenes by an Amide Base Generated in Situ from Tetramethylammonium Fluoride and Tris(trimethylsilyl)amine


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  • M. Shigeno, Y. Fujii, A. Kajima, K. Nozawa-Kumada, and Y. Kondo, "Catalytic Deprotonative α-Formylation of Heteroarenes by an Amide Base Generated in Situ from Tetramethylammonium Fluoride and Tris(trimethylsilyl)amine", Organic Process Research & Development, vol. 23, pp. 443-451, 2018. http://dx.doi.org/10.1021/acs.oprd.8b00247
  • Scalable Continuous Flow Process for the Synthesis of Eflornithine Using Fluoroform as Difluoromethyl Source


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  • M. Köckinger, C.A. Hone, B. Gutmann, P. Hanselmann, M. Bersier, A. Torvisco, and C.O. Kappe, "Scalable Continuous Flow Process for the Synthesis of Eflornithine Using Fluoroform as Difluoromethyl Source", Organic Process Research & Development, vol. 22, pp. 1553-1563, 2018. http://dx.doi.org/10.1021/acs.oprd.8b00318
  • Intermolecular Reductive C–N Cross Coupling of Nitroarenes and Boronic Acids by PIII/PV═O Catalysis

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  • T.V. Nykaza, J.C. Cooper, G. Li, N. Mahieu, A. Ramirez, M.R. Luzung, and A.T. Radosevich, "Intermolecular Reductive C–N Cross Coupling of Nitroarenes and Boronic Acids by PIII/PV═O Catalysis", Journal of the American Chemical Society, vol. 140, pp. 15200-15205, 2018. http://dx.doi.org/10.1021/jacs.8b10769
  • Development of a Large-Scale Copper(I)/TEMPO-Catalyzed Aerobic Alcohol Oxidation for the Synthesis of LSD1 Inhibitor GSK2879552


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  • A. Ochen, R. Whitten, H.E. Aylott, K. Ruffell, G.D. Williams, F. Slater, A. Roberts, P. Evans, J.E. Steves, and M.J. Sanganee, "Development of a Large-Scale Copper(I)/TEMPO-Catalyzed Aerobic Alcohol Oxidation for the Synthesis of LSD1 Inhibitor GSK2879552", Organometallics, vol. 38, pp. 176-184, 2018. http://dx.doi.org/10.1021/acs.organomet.8b00546
  • Rapid Structure Determination of Microcrystalline Molecular Compounds Using Electron Diffraction


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  • T. Gruene, J.T.C. Wennmacher, C. Zaubitzer, J.J. Holstein, J. Heidler, A. Fecteau-Lefebvre, S. De Carlo, E. Müller, K.N. Goldie, I. Regeni, T. Li, G. Santiso-Quinones, G. Steinfeld, S. Handschin, E. van Genderen, J.A. van Bokhoven, G.H. Clever, and R. Pantelic, "Rapid Structure Determination of Microcrystalline Molecular Compounds Using Electron Diffraction", Angewandte Chemie International Edition, vol. 57, pp. 16313-16317, 2018. http://dx.doi.org/10.1002/anie.201811318
  • One‐Pot Synthesis of Aryl‐ and Alkyl S‐Perfluoroalkylated NH‐Sulfoximines from Sulfides



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  • S. Chaabouni, J. Lohier, A. Barthelemy, T. Glachet, E. Anselmi, G. Dagousset, P. Diter, B. Pégot, E. Magnier, and V. Reboul, "One‐Pot Synthesis of Aryl‐ and Alkyl S ‐Perfluoroalkylated NH ‐Sulfoximines from Sulfides", Chemistry – A European Journal, vol. 24, pp. 17006-17010, 2018. http://dx.doi.org/10.1002/chem.201805055