chemical_biology

Biocatalytic in Vitro and in Vivo FMN Prenylation and (De)carboxylase Activation

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ACS Chemical Biology

ACS Chemical Biology: Latest Articles (ACS Publications)
Authors: Khorcheska A. Batyrova†‡?, Anna N. Khusnutdinova†‡?, Po-Hsiang Wang†§?, Rosa Di Leo†, Robert Flick†, Elizabeth A. Edwards†, Alexei Savchenko†?, and Alexander F. Yakunin*†#
feedproxy.google.com/~r/acs/acbcct/~3/C99DyWuRD2w/acschembio.0c00136

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Identifying the Target of an Antiparasitic Compound in Toxoplasma Using Thermal Proteome Profiling

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ACS Chemical Biology

ACS Chemical Biology: Latest Articles (ACS Publications)
Authors: Alice L. Herneisen†‡, Saima M. Sidik‡, Benedikt M. Markus‡§, David H. Drewry??, William J. Zuercher?, and Sebastian Lourido*†‡
feedproxy.google.com/~r/acs/acbcct/~3/WJrXkN42d-c/acschembio.0c00369

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Discovery of Novel Antibiotics as Covalent Inhibitors of Fatty Acid Synthesis

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ACS Chemical Biology

ACS Chemical Biology: Latest Articles (ACS Publications)
Authors: Jia Wang†, Xiaoping Ye†, Xiaohan Yang†, Youyan Cai†, Shengjun Wang†, Jieyu Tang†, Meena Sachdeva§?, Yu Qian†, Wenhao Hu†, Jennifer A. Leeds§?, and Yanqiu Yuan*†‡
feedproxy.google.com/~r/acs/acbcct/~3/QPv0V_l8I5g/acschembio.9b00982

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Aromatic Cytokinin Arabinosides Promote PAMP-like Responses and Positively Regulate Leaf Longevity

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ACS Chemical Biology

ACS Chemical Biology: Latest Articles (ACS Publications)
Authors: Magdale´na Bryksova´†?, Siarhei Dabravolski‡?, Zuzana Kuc?erova´§?, Filip Zavadil Koka´s?‡?, Martina S?pundova´§, Lucie Pli´halova´†?, Toma´s? Taka´c?#, Jir?i´ Gru´z?, Martin Hudec?ek?, Veronika Hlous?kova´?, Radoslav Koprna†, Ondr?ej Nova´k?, Miroslav Strnad?, Ondr?ej Pli´hal*‡?, and Karel Dolez?al†?
feedproxy.google.com/~r/acs/acbcct/~3/SW_FCguQgVo/acschembio.0c00306

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Inhibiting Protein Prenylation with Benzoxaboroles to Target Fungal Plant Pathogens

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ACS Chemical Biology

ACS Chemical Biology: Latest Articles (ACS Publications)
Authors: Sang Hu Kim†, Chunliang Liu‡, Yasheen Zhou‡, Yong-Kang Zhang‡, Cari McGregor‡, Luke Steere‡, Brittany H. Frederick‡, C. Tony Liu‡, Luke Whitesell†, and Leah E. Cowen*†
feedproxy.google.com/~r/acs/acbcct/~3/SnXrBD4rWNc/acschembio.0c00290

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Substrate Plasticity of a Fungal Peptide a-N-Methyltransferase

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ACS Chemical Biology

ACS Chemical Biology: Latest Articles (ACS Publications)
Authors: Haigang Song??‡, Ju¯rate` Fahrig-Kamarauskaite`†‡, Emmanuel Matabaro†, Hannelore Kaspar†, Sally L. Shirran§, Christina Zach†, Amy Pace†, Bozhidar-Adrian Stefanov†, James H. Naismith*???, and Markus Ku¨nzler*†
feedproxy.google.com/~r/acs/acbcct/~3/cn_6kHE2LJY/acschembio.0c00237

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The Stereocontrolled Biosynthesis of Mirror-Symmetric 2,4-Diaminobutyric Acid Homopolymers Is Critically Governed by Adenylation Activations

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ACS Chemical Biology

ACS Chemical Biology: Latest Articles (ACS Publications)
Authors: Kazuya Yamanaka*†, Hibiki Fukumoto†, Munenori Takehara‡, Yoshimitsu Hamano§, and Tadao Oikawa†
feedproxy.google.com/~r/acs/acbcct/~3/XbJQGQm5twQ/acschembio.0c00321

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RASS‐Enabled S/P–C and S–N Bond Formation for DEL Synthesis

Flood, Baran, Dawson et al.

[1]

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  • D.T. Flood, X. Zhang, X. Fu, Z. Zhao, S. Asai, B.B. Sanchez, E.J. Sturgell, J.C. Vantourout, P. Richardson, M.E. Flanagan, D.W. Piotrowski, D.K. Kölmel, J. Wan, M. Tsai, J.S. Chen, P.S. Baran, and P.E. Dawson, "RASS‐Enabled S/P−C and S−N Bond Formation for DEL Synthesis", Angewandte Chemie, vol. 132, pp. 7447-7453, 2020. http://dx.doi.org/10.1002/ange.201915493
  • Structure-Guided Design and In-Cell Target Profiling of a Cell-Active Target Engagement Probe for PARP Inhibitors

    Astra-Zeneca

    [1]

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  • R.T. Howard, P. Hemsley, P. Petteruti, C.N. Saunders, J.A. Molina Bermejo, J.S. Scott, J.W. Johannes, and E.W. Tate, "Structure-Guided Design and In-Cell Target Profiling of a Cell-Active Target Engagement Probe for PARP Inhibitors", ACS Chemical Biology, vol. 15, pp. 325-333, 2020. http://dx.doi.org/10.1021/acschembio.9b00963
  • Heterobifunctional Molecules Induce Dephosphorylation of Kinases–A Proof of Concept Study

    Genentech – Pharmaron
    [1]

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  • S. Yamazoe, J. Tom, Y. Fu, W. Wu, L. Zeng, C. Sun, Q. Liu, J. Lin, K. Lin, W.J. Fairbrother, and S.T. Staben, "Heterobifunctional Molecules Induce Dephosphorylation of Kinases–A Proof of Concept Study", Journal of Medicinal Chemistry, vol. 63, pp. 2807-2813, 2019. http://dx.doi.org/10.1021/acs.jmedchem.9b01167